Stir-Fried Stochasticity Ep 04 (“TuberculosisBurgers”) is up…

Oh, I forgot to mention here that Episode 4 is up at http://www.dogphilosophy.net, where I’m trying out the “Powerpress” plugin for WordPress to see how it works out. Please give it a listen and let me know how it is.

I’m still plotting to expand out to three different podcasts/oggcasts or so, including of course the current Stir-Fried Stochasticity podcast (Science news direct from primary sources: scientific publications), an intermittent “Perceptive Peripatetic” series literally based on random things that I happen to run into as I wander around which happen to amuse, interest, or inspire me, and a “The Computer Is My Friend” free-fun-with-computer-nerd-stuff podcast. Upcoming episodes being considered for each include:

    Stir-Fried Stochasticity

  • Episode 5: This Episode Is Garbage (concerning Landfills)
  • Episode something-higher-than-5: “Two Mass Spectrometers, High Performance Liquid Chromatography, and a Female Donkey” (concerning exactly what it says…)
  • Episode also-something-higher-than-5: “Is there anything Beer cannot do?” (concerning some interesting beer-related publications I’ve collected)
  • Various other papers from various fields have also been collected for consideration. Suggestions are welcome.

    Perceptive Peripatetic

  • “The Firebreathing All-Devouring Skybeast of the Gulf” (inspired by a photo I took recently, if I can get it to turn out the way I want it.)

    “The Computer Is My Friend”

  • Episode 01: “Freetarded” podcasting (concerning practical, ethical, legal, and technical stuff I’ve run into and considered while trying to support this new podcasting hobby of mine – hopefully useful for anyone else interested in producing their own audio and/or video for the web and for public participation.)
  • Episode sometime-after-01: “Enterprise Linux Must Die” (Tentative plot: it’s actually “pro-Linux” but is a rant against “Enterprise” distributions, or at least one in particular, and some praise for “rolling releases”).
  • Episode also-sometime-after-01: “Freetarded” mobility (concerning Android, Meego/Maemo, and my quest to get as much functionality on my cellphone while remaining as “Legally Free” as possible. Might possibly include instructions for making an external microphone adapter for various cellphone models, and might also include some (optional) video content.
  • Episode yet-another-sometime-after-01: Where? (Concerning geolocation, geolocated digital photos, other geolocated media, “geotagging” in general, and some verbal chastisement for people who say they are “geotagging” but [in my opinion] are not.)

The schedule for all this is still unspecified (but far quicker than “another year” until the next episode, at least), and as usual is heavily influenced on what anybody who is willing to listen might be interested in. I may be doing this for fun rather than profit, but the fun will be greatly enhanced if I’m not just sitting here talking to myself. Feel free to post in the comments (anonymously if you prefer – just put a fake email address in the field that asks for it.)

The Breakdancing Ghost of Narada Falls

Gather around the campfire, boys and girls and everyone else. It’s story time.

(This is both an attempt to entertain AND a technical test – I’d be most appreciative if any or all of you left me a comment letting me know how this works for you. I’ll put some technical information at the end of the post.)

This story concerns a certain location in Mount Ranier National Park…

http://www.panoramio.com/photo/38235159After you hear this harrowing tale, if you can’t make it out to Mount Ranier National Park to verify the story for yourself, you can see a picture of the monument online. Click or scan the QRCode image to the right to see it after you’ve heard the story.

Feedback is welcome and encouraged. For those who are interested, here’s what this post is supposed to do, technically:

If you are viewing this post in a modern (HTML5-supporting) browser, the “native” audio player in your browser should appear above, allowing you to press “play” and listen to the story. All but one of the modern HTML5-supporting browsers support the high-quality (and legally free to use) “Ogg Vorbis” audio format and will play that version. If you are in the minority of HTML5-browser-using population (Safari), an MP3 version should play instead. (The problem with Safari is that Apple doesn’t include a Quicktime component for Ogg media formats out of the box. Personally, I would recommend going ahead and installing the Free Quicktime Components, which will enable Ogg media formats for Safari, iTunes, and all other Quicktime-using programs.)

If you are NOT using a modern, HTML5-supporting browser at all (or are perhaps using one I’ve never heard of that supports neither higher-quality Ogg Vorbis nor MP3) – mainly Microsoft’s “Internet Explorer” browsers and really old versions of Firefox or Opera that may still be in use – if you have Java installed, a Java-based Ogg Vorbis player should appear instead, allowing you to play the higher-quality audio anyway.

If your browser doesn’t support HTML5 AND doesn’t support Java, a link to an Adobe Flash-based MP3 player should appear. Click on that, and you SHOULD have a window pop up that will play the lower-quality MP3 version of the audio.

In short, nearly everyone should be able to play the audio if I’ve done all of this correctly. Please let me know.

Amateur Soap Microbiology and my new Friend

I thought soap was supposed to be *clean*!

lumpy yellow microbial colonies growing on the soap inside of a hand-soap dispenser
People usually assume soap gets rid of funky microbes that might grow on things, so I was very amused several months ago when I spotted something growing on top of the soap in one of the household hand-soap dispensers. As of today, it looks as pictured at left. That lumpy yellow and brown mass atop the the soap looked to me like some sort of soap-sodden mold, and have been saving the dispenser specifically in the hopes that someday I’d have a microscope and could take a look at it. Meanwhile, the mass spread, and slowly started releasing some kind of yellow pigment into the soap.

Incidentally, I kind of doubt this indicates some sort of failure on the part of the manufacturer of the soap. I don’t recall for certain, but I think I may have opened the dispenser at one point to transfer some of the soap to another nearly-empty dispenser. When the mass started growing originally, it was a single spot, which suggests a single spore or speck of dust floating in and landing on the surface. Hey, it happens. Anyway, I’ve therefore blanked out the name of the manufacturer since I don’t think they really have anything to do with this.

VWR VistaVision Microscope
This mysterious growth upon my soap remained mysterious until today. Thanks to the Minister of Domestic Affairs and VWR (who managed to find me a really good deal), I finally got to actually get a close look at that lumpy mass. Meet my new friend Minnie (pictured at right). I could gaze into those eyes for hours. I couldn’t afford a darkfield condenser, and I sure as heck couldn’t afford to upgrade to phase-contrast gear, but I can add either one later if the opportunity presents itself. I also can’t afford the overpriced proprietary digital camera attachments either, though working around that is a whole other project. Until I identify an affordable model that plays well with Linux or work out how to modify a webcam into an ocular attachment,
I’ll have to settle for a trick…

It turns out if you take a digital camera and set it for close-up photos, you can actually stick the camera lens right up to the eyepiece and often get a serviceable picture.. Now, I had to subject the pictures I got today to moderately heavy processing to bring out the detail a bit better, but at least part of that is just me working on learning how to optimize the camera settings for this kind of use.

Equipped with some surplus slides and cover-slips donated by a kind professor who had some extra packages, I opened up the soap container and smeared a little of the yellow crud on a couple of them. One I just slapped a coverslip on for direct observation – the other I smeared over a slide and let dry with the intention of staining using the tiny, previously-unused vial of methylene blue left over from a very old plastic toy microscope. While the latter dried, I took a look at the wet mount hoping to finally see the mold mycelia that I had been expecting…

There wasn’t enough contrast to bother trying to get a photo, but it was obvious at 400x that what I was looking at was bacteria, not mold. Nerdly joy at learning something by looking in the microscope that I wouldn’t have otherwise known ensued, along with happiness as I realized this meant I had a perfect excuse to dig out my recent shipment from the Maker Shed – materials for doing a “Gram Stain”. Incidentally, the “Maker Shed” had the supplies on the way to me within hours of my ordering it, and they have lots and lots of cool stuff. I highly recommend it. Anyway, I got to do a “Gram Stain” for the first time in a couple of years (and the first time ever outside of a school lab). Want to see?

Mystery Microbe, I see you!

Gram-stained bacteria
Here it is – the nasty yellow goo that infected my bottle of hand-soap. My staining technique was a little off since I’m out of practice – the way I interpret the results is that what I’ve got here is neither a member of the Firmicutes (i.e. “Gram positive”) nor – probably – Actinobacteria. I really can’t guess at more than that, though. I think the few “Gram-positive”-looking cells there are artifacts of insufficient decolorization. I know I still had a surplus of the purple “Crystal Violet” stain still on the slide at the end. (How did I know? I’ll show you at the end…). The irregular bluish bits towards the bottom are, I believe, just bits of stuff from the soap itself.

Meanwhile, this pretty much satisfies my curiousity about the Mystery Soap-Infecting Microbe. There’s certainly a lot more I could investigate, but my developing Hillbilly Biotech lab is really intended to support my interest in intentional food microbiology and perhaps evenutally some small-scale non-food industrial microbiology. I have some remaining curiousity about the yellow pigment and whether or not it might be useful for something, but I’m doubting there is any food or beverage I might want to grow this stuff in and therefore don’t have much use for it. Still, I’ll keep the bottle around for a while before I throw it out in case I think of something fun to do with it. If I end up being really interested in the identity of the bug growing on it, I should be able to find a liquid that I can grow a big mess of it in, then run it through a simple DNA extraction process. Then all I need to do is find someone who can supply PCR primers, a thermocycler, and sequencing services cheap. It might sound like I’m being facetious, but I wouldn’t be surprised these days if I manage to find somewhere that’d do it for $20/sample or less. I may eventually do this will the Mystery Soap Bug anyway, since I hope to be running through this process with cultures of sourdough, yogurt, cheese, vinegar, and brewing microbes that I develop myself. For now, though, it’s just nice to be playing with microbiology equipment again. And now fully independently! Wheeeeeeee!!!!!!

Yes, I’m a nerd. And proud of it!

What’s next?

Now that I finally have a microscope, I no longer have any excuse for not getting to work on the rest of my Hillbilly Biotech lab. Just this weekend I was pricing out Hillbilly Autoclaves. I picked up a cheap air pump and air stone
for potentially building an aerobic bubble-column fermenter (for quick growth of yeast starters or a working model of a “Fring’s Acetator®”-style vinegar generator. I still want to build an ozone generator for sanitization and to get a pH meter. I’d like to also get my hands on some wheat, barley, and rye seeds to sanitize, sprout, and grow here as the first stage of developing a truly local sourdough culture, plus arrange to have several pounds of plain flour irradiated to sterilize it.

I’m also like summer to be over. Yes, I’m writing this in Winter, but it’s not until later in the summer to autumn that locally-grown fruits will start becoming available, and locally grown fruits ought to be an ideal source of local brewing and baking yeasts and bacteria. Finally, I’d like to find a wealthy patron (or matron, I’m no sexist…) who would sponsor me so I could just pursue food-microbe bioprospecting and research full-time…

Oh, yes, and I need to get around to finishing Episode 4 of my little podcast project, especially since episode 4’s topic is a fundamental microbiology technique.

Comments welcome below – thanks for reading!

Oh, and as a reward for getting all the way to the end, here’s a picture that I thought was pretty – crystals of “Crystal Violet” and iodine. I told you I had too much left on the slide…
Crystallized dye left on the slide

The Maker Shed is Moderately Awesome

I’ve got two blog posts that I want to get done this weekend. This is one of them.

I’m something of a fan of MAKE magazine and its related websites and such, being a frustrated “Maker” and all. “Frustrated” because although I have a strong urge to make things, I seem to have a gross oversupply of chores and issues constantly popping up to keep me from getting much done. Still, I try, despite the efforts of the Dog and five (insert mild profanity here) cats (I seem to have been declared the household “Stuff that goes into and comes out of nonhuman mammal companions technician”), and living space that thinks it’s necessary to demonstrate how entropy works on a constant basis. MAKE’s slogan is “If you can’t open it, you don’t own it”, which I so passionately agree with that I wish they were a political party so I could vote for them.

Anyway…MAKE magazine recently posted a poll asking for opinions on the magazine, the website, and so on. The way the poll was structured didn’t really let me address what I really like and dislike about the site, so I thought I’d post it here in case anyone besides me is interested.

But first, some praise: part of the poll was asking about the online store they run – The Maker Shed. I filled in the poll just a day or so before I went and ordered something from it, so I couldn’t give any opinion of it at the time. Having now gotten what I ordered, I have to say the store seems to be moderately awesome.

One of my complaints about the MAKE franchise is that it often seems to be made entirely of Arduino™ electronics, Arts-and-crafts (e.g. knitted things), and baking-soda-volcano sorts of projects for children. In truth it’s not that bad, but I would personally like to see “less Arduino™, more ‘Bioreactor’” – they actually published a “Bio-hacking“-themed issue a while back, so there’s hope. I bring this up because what they had at the Maker Shed that I bought was microbiological staining supplies (not actually the kit pictured above, but they didn’t have pictures of individual bottles of what I got). I put in my order online expecting it to be shipped the next business day, and was pleasantly surprised to find an “okay, you’re order’s been shipped” notice in my email within an hour or two. The stuff even arrived by that weekend (i.e. today), hopefully leaving me time to use it for my planned second blog post of the weekend. So, definitely fast service at the Maker Shed.

There are a few annoyances I have with the MAKE franchise, though:

  • Their “pod®casts” appear to all be videos (no audio-only podcasts at all)
  • I’d actually really like to have actual no-video-required audio shows that I could listen to on my 2½-hour daily commute. Not all of us want to (or can!) sit and stare at computer and/or “iPod®” video screens but still would like regular infusions of MAKE-related news and information.

  • The videos appear to be all presented in proprietary Apple® formats or proprietary Flash on youtube.
  • This isn’t a major technical problem for me – Mplayer handles the files just fine. However, given that Apple’s preferred formats are all heavily patent-encumbered and proprietary and therefore not really legally usable for “making” video without special paid-for permission from Apple® corporation, it seems an odd choice for the “If you can’t open it you don’t own it” folks. Perhaps they’re just paranoid that Steve Jobs is lurking just on the other side of the bay, waiting for an excuse to come up there and kick their butts if they aren’t pro-Apple® enough? In any case, I’m kind of surprised they seem to have no interest at all in legally-free, amateur-multimedia-maker friendly formats like Vorbis and Theora.

  • Where are the “Food and Drink” issues of MAKE?!?!? (And I don’t mean an Arduino®-controlled Lego® motorized model of a carnivorous cupcake or something, I mean actual edible food and potable brews. Not that “Killer Lego Robot Cupcake” wouldn’t be kind of neat….)
  • There’s enough “kids stuff” to split off into its own publication
  • Or so I believe, anyway. They already split the arts-and-crafts stuff off into its own CRAFT magazine. If they also split off the “make a paper plate toy” stuff to “Make: Kids” (Wait, “making kids” sounds like some kind of pornographic euphemism. Make that “Kids: Make”) there’d be more room for the more hardcore stuff (and a higher chance of more stuff I’m personally interested in).

  • It doesn’t seem like you can log in to comment on the Make blog without an account somewhere else (I USED to have a login directly on the site from when it first started, but that login no longer seems to work and the login screen implies the need to login through some other site’s service. Time to look up how to set up my own OpenID server…)
  • The Maker Faire always seems like it’s awesome but I can never go.
  • This isn’t really MAKE’s fault, unless they’re part of the secret cabal that conspires to keep me from having enough wealth and leisure time to attend things like this.

  • I can’t get this dang cat to quit jumping on my lap while I’m trying to type.
  • Okay, this has nothing to do with MAKE, but it’s annoying me right now.

There – now I’ve gotten it out of my system and out here where if anybody actually cares they can see it. Just some stuff that there was no way to convey in the survey. Otherwise I highly recommend MAKE magazine and its associated online material. The world needs more Makers and they’re doing some spiffy stuff to help in Sebastopol these days.

Now then, if all goes well I should have another post tomorrow with some pretty pictures of soap. Stay tuned…

YOU DANG KIDS GET OFFA MY LAWN!

Looks like the truckloads of candy-seeking larvae are done finally. Wretched little urchins now get driven from block to block rather than walking the neighborhood like we did.

(It doesn’t actually bother me as much as that makes it sound, I just like having an excuse to say “wretched little urchins”…which reminds me – I have only about a month to get a cheerful flashing “Bah! Humbug!” sign built…)

The only thing that really annoyed me is the fact that having to be ready to be interrupted by another horde of costumed consumers meant I couldn’t really spend any of the evening getting into anything requiring any real attention…which means the 113g of CaCl2.2H2O I’ve got sitting here now to go with my Xanthan Gum has been left neglected, and I still don’t know if I can make Xanthan Gum gel into beads the way you can with sodium alginate. I figure it must be possible, given that both Xanthan gum and Alginate (among others) were all formed into little “bio-booger” beads using the same kind of process in the paper I discussed in Episode 2 of my little audio oggcast. Perhaps I’ll have time to find out tomorrow.

For now, it’s time for bed. Daylight Losings Time starts tonight, so if the critters allow me to actually sleep, I ought to be well rested to attempt some serious lake-spanking in the morning – there’s supposedly a resort on the shore of the lake that has a sushi bar, and the idea of being able to paddle out for sushi amuses me. It looks like it’s at least 9-10 miles away, though, so it’ll be a long trip if I attempt it. Hopefully I’ll have time left after that.

Also, the developer of the libdmtx datamatrix barcode encoder and decoder software posted a recent comment on my previous post about the software and its potential uses – looks like some interesting projects going on there, including one intended to generate ID cards that only legitimate authorities could read (so as to prevent identity theft).

P.S. Anybody know how to build a really good (but simple) ozone generator for sanitization purposes? Or the effective pore sizes of commonly available materials like plastic wrap? Or if a corporate entity can be a shareholder/partner in a Limited Liability Company?

Don’t forget to feed and walk your mitochondria

Yes, I’m still here – though I don’t know if any of YOU are.

The pay at my job is somewhat low for the skillset it requires, but makes up for that by having a very reasonable workload, a pleasant work environment, and certain perks – like access to the electronic journals that my employer subscribes to. I added an RSS feed from pubmed intended to cover my main interests – basically edible and industrial microbiology and biotechnology. Every day, a list of 300-600 or so new scientific articles pops up in my feedreader and I scan through the titles looking for anything interesting to me. Unintentionally, my selection appears to also result in quite a bit of diabetes, obesity, and sports medicine research. Lately I’ve taken a moderate interest in our own most blatantly bacterial components, the mitochondria.

Mitochondria are kind of like a nearly 2-billion-year-long case of typhus (or Rocky Mountain Spotted Fever, if you prefer). After infecting our ancestors (and now us) for so long, they’ve been reduced to dependency on living in our cells. Perhaps a bit like the progression from wolves to Chinese Crested dogs. On the other hand, having thoroughly domesticated them, we get a lot of use out of them, and couldn’t live without them. Their ability to harness the electron-sucking power of oxygen means we get almost 20 times more energy out of our food than we otherwise would, which is a good thing since biologically speaking, keeping the hideously complicated mess of biochemistry that makes up a human body takes a ridiculous amount of biochemical energy compared to that of normal organisms (i.e. prokaryotes).

Lately in the stream of new publications I’ve been seeing a number of papers suggesting that a lack of proper mitochondrial activity might be related to obesity and related problems (e.g. “metabolic syndrome”, type 2 diabetes and insulin resistance, obesity-related “inflammation”, and so on) and even some age-related problems, both physical and mental. There is some seriously interesting research going on into treatments to potentially stimulate mitochondrial activity and whether this might help solve a number of health problems.

So…take good care of your mitochondria. For the past couple of weeks I’ve been trying to pay special attention to properly feeding my mitochondria and making sure I take them for regular walks (and paddling trips and so on). It could, of course, be purely psychosomatic, but right now I feel better than James Brown

There’s a fair amount of rational skepticism over using drugs or nutritional supplements to stimulate mitochondria, but here’s a tip that I suspect everyone’s doctor would accept: make sure you take your mitochondria for regular walks. Frequent exercise (particularly endurance exercise) seems to be a scientifically well-accepted way to induce production of more mitochondria.

But now I have to go to bed. My main complaint with work these days is that it eats up essentially my entire day, leaving me with just enough time for some household chores between getting up in the morning and going to bed in the evening. Not their fault I live almost and hour and a half from work, though (and at least the commute is through relatively low-traffic and scenic terrain.). Still, it makes it hard to get blog posts and podcasts done (episode 4, on the subject of “heat-fixing” of bacteria for microscopy – particularly Mycobacterium tuberculosis – will be out as soon as I can manage. Still pondering the subject of Episode 5. I’m saving the “Two Mass Spectrometers, High Performance Liquid Chromatography, and a Female Donkey” episode for later when I manage to surpass the “nearly 3” listeners that I seem to be stuck at…)

“Stir-Fried Stochasticity” podcast: pilot episode

Cornelia the Happy Mutt with a tennis ballI’m still not sure I know why I have a desire to push recordings of my voice onto a more or less innocent worldwide population, but I do. And now I have a real theme to wrap an attempt at a podcast (or as I prefer – “oggcast”) around: scientific papers.

I finally got annoyed at press-release-based science stories one too many times, and thought to myself “why does almost nobody who does these stories at least cite the dang thing so I can go look it up and see what’s really in it, if they can’t be bothered to actually read and report on it themselves rather than just the press-release?” The story in question was the recent one about how babies understand dog-language (or something like that). Since I consider the dog to be a philosophical role-model, I wanted to read the actual paper and see if it was as silly as the headlines made it sound or (as I suspected) less flashy but more solid…but even “Science Daily” didn’t cite it.

Finally talking myself out of putting off doing audio recording, I tracked down the original paper, read it, and whipped out a rough show discussing what I found in the paper. I had fun doing it, so I’d like to turn it into a series.

I’ve put up a utilitarian page at http://bigroom.org/stirfry with both a built-in <audio> tag interface and direct-download links for both Ogg Vorbis and MP3 versions.

I’m still deciding exactly how I’m going to decide on the papers to cover – should I pick obscure, forgotten ones that almost nobody else would ever read again without me stumbling on them and talking about them? Classic papers? Papers related to recent news stories like this one? All of the above? Depending on how long I end up trying to make the episodes, perhaps starting with some kind of scientific question and then reporting on a selection of papers I dig up to address the question, or just a selection of papers on the same subject? I’ve already gotten a request for an episode on the theme of prokaryotic extracellular polysaccharides…

The rate at which I can convince myself to try to crank these out (and improve their quality) is directly proportional to how much interest there might be out there in them, so please don’t hesitate to let me know if you think this might be interesting. Please don’t let me slack off! Also, feel free to correct me if I’m wrong about anything I mention in the show or the attached show notes.

If you don’t want to comment here, you can also email me at epicanis at bigroom.org.

Thank you, and good night…

Firefox, Bacteria-snot, and job-hunting geologist

'Human Statue' striking a constipated looking pose on a toiletI have to say that suffering through periods of chronic blogstipation is seriously annoying.

There have been a number of things I’ve been wanting to post about, but I’ve been way too loaded down to have time to sit down and compose them. Therefore, lest anyone think I’ve abandoned bigroom.org, I’ll throw a few of them out here in shortened form.

First, a public service announcement: HTML 5 is not just about turning the internet into Television. I keep seeing articles about “HTML5” and they all seem to focus obsessively on the <video> tag. The same is largely true of articles about the recent Firefox 3.5 browser release, since arguably the biggest feature of the new version is HTML5 support. Although there are quite a few other new features, the main one I wanted to briefly remind everyone of is that there’s also an <audio> tag. I think audio is important, because it’s a lot simpler for people to generate audio for the web than to produce a video. Also, the “Vorbis” audio codec is a definite step up in quality from the de-facto “mp3” codec. The latest Opera, Google Chrome, and Firefox browsers all support the <audio> tag with “Ogg Vorbis” files. Apple’s Safari browser doesn’t by default, but that’s easily fixed. If you install the free QuickTime® component from Xiph, it teaches QuickTime about Ogg files, allowing you to watch and listen to the same HTML5 audio and video that everyone else (aside from Microsoft, as usual) can. It apparently also allows you to create Ogg files through QuickTime, so you can make your own content available for everyone else to watch and hear if you want to.

If you’ve seen some of my earlier map-and-pictures posts, you can probably guess that I’m also interested in the new geolocation feature. As far as I can tell, it’s currently natively implemented in the new Firefox, but will be showing up in Safari, Opera, and Chrome (at least) in the relatively near future. My only real complaint is that right now Firefox can only get the location through Google via your current IP address, and that isn’t at all accurate (when it works correctly, the precision is limited to “somewhere around this city” – when it doesn’t, where it thinks you are depends entirely on whose network your internet connection comes from.) It’s still baffling to me why they didn’t include a simple “manual entry” option for geolocation. Anyway, I’ve not had time to dig into this either, so enough said about that. For now.

And now a question of science and microbiology enthusiasts who may read this – I may soon, finally, be able to buy a microscope. Any recommendations on where to get one? The only “special” features that I really want (and can afford) would be a sufficiently bright light source and ability to swap in a darkfield condenser from time to time.

Penultimately, bacteria snot Xanthan Gum is hereby declared my Favorite Food Additive of the Month. It turned out to do exactly what I hoped it would do in the lemon-ginger ice cream I made a couple of weeks ago. I must play with this delightful edible substance more.

Finally, is anybody in California actually hiring geologists? As if marrying me wasn’t proof enough of insanity, my wife really wants to move back there. We can’t stay here forever in Southeast Texas on just my meager academic staff salary, as nice as the job itself is, and although for months she’s been firing off applications all over the country (and even a few beyond the borders) she’d really prefer to take her geophysics experience and PhD in Geology from UC Davis back to California. Although I’m personally a bit less enthusiastic about the idea, the possibility of getting into UC Davis’ Fermentation Science or Food Science graduate programs definitely has some appeal. Plus, I’d be able to listen to This Week In Science live while it’s being broadcast.

This Week = No Fun, but here’s an update anyway…

Busy week with unpleasant surprises, but I ain’t dead yet. You’re probably wondering what a hot dog that’s apparently eagerly anticipating eating itself has to do with that. The answer is: nothing, but it does relate to something I have been intending to post about for a long time, but haven’t since I didn’t have access to the paper…

So, in lieu of blasting out Twitter®-style updates on my Laconica feed that nobody reads anyway (a few people no doubt see the echo of them on Twitter® itself, but I don’t know if anyone cares…), here are a couple of what-I’m-doing-now updates before I go to bed:

  • I just shot off an email to the webmaster (the only contact I could find who might have the relevant information) of the Institute of Brewing and Distilling, trying to get access to a classic paper published in the Journal of the Institute of Brewing and Distilling for the upcoming “On the Shoulders of Giants” carnival.
  • There’s no way I can afford the ~$300US that it would cost to join the group, nor even at the moment to pay the typical $30 or so that greedy paywall-imprisoned publishers charge for individual articles. However, they appear to be opening up their archives to the public, for which I think they deserve substantial praise. Still, they haven’t worked their way back to the first few decades of the 20th century yet, so I had to email and ask if there was a way to get the article in question. If not, I’ll see if there’s any way to get it through inter-library loan in time.

  • “Small Things Considered” asks “What Microbiological Discovery in 2008 Did You Find Especially Interesting?” Which brings us to the “self-eating” thing.
  • The paper on caffeine’s induction of macroautophagy (“self-eating”) in yeast (and what happens when benzoic acid is also present) finally escaped from the paywall prison in January, and I now have a copy. I at least thought it was full of interesting implications (along with some useful knowledge), so I’ll hopefully be posting about it soon.

  • I’m also a computer nerd
  • Particularly when it comes to things like Linux. I’ve been thinking of trying to do some recordings on a couple of practical subjects that interest me for “Hacker Public Radio”

  • And of course, I still need to do some Xanthomonas snot Xanthan Gum experiments.

I am an attention-whorewilling to listen to my readers’ interests, so if anyone has suggestions or comments feel free to post them…

Oh boy. This is “bad”.

(Note the “scare quotes” around “bad” up there…)I woke up kind of late this morning, which is probably just as well as I think I really needed the sleep before I load up the car with stuff from the old house and make the ~1600 mile (about 2575km or 83.45 picoparsecs) return journey. As a bribe to myself for making this trip, there are two places I had been considering stopping for a bit on the way back. One of those two is New Belgium Brewing Company in Fort Collins, Colorado. In order to do this, though, I obviously need to arrange to be going through Fort Collins (around 8-9 hours from here) while they’re open. The thing is, there’s really not much point in stopping from my perspective unless they happen to have what I’m really interested in – their not-always-available limited-release “La Folie” (link from the image goes to the page describing it) and possibly their seasonal “Frambozen“. Last time I went by it appeared they always had some La Folie on tap at the tasting counter but not in bottles for take-out.

It turns out New Belgium is open on Saturday until 6pm. And they have both La Folie and Frambozen in bottles there right now.

The other possible stop is Lava Hot Springs, Idaho, where I find it very enjoyable to lounge in the hot springs amid all the snow. However, they open at 9am, so even if I get up really early to make it to Fort Collins before New Belgium closes, I can’t spend any time in the hot springs until 9am anyway, so I’d never make it from the Hot Springs to Fort Collins on the same day. I could, of course, lounge at the hot spring today and then hit Fort Collins tomorrow morning, stopping somewhere between Central Wyoming and Fort Collins tonight, but that could mean the return journey spanning three days rather than two.

However, the weather on this side of Idaho and Wyoming looks most passable today especially later in the afternoon when the roads have been cleared off well, and it looks like getting across the bad wind and snow on the Eastern side of the Wyoming may be safer and better tomorrow morning rather than today.

So, basically, the entire Universe (or at least that portion of it in charge of weather for this region of the country) is obviously telling me that I should take my time loading up and getting out of town, and then go ahead and stop at Lava Hot Springs for a little while to relax before continuing on to somewhere around Rawlins or so, and then resume in the morning which should just coincidentally put me going through Fort Collins in the Late-Morning to Early Afternoon time frame, when New Belgium Brewing is open.

I mean, I don’t want to stop and enjoy myself. Really, I want to be a good boy and drive back in the quickest, most efficient way possible, but who am I to thwart what is the Obvious Will of the Universe? (Supernaturalism makes some of the best excuses…)

In other news, I did manage to fix the Stupid Mistake™ in my little “Where Was I?” application for Asterisk, so now not only do the location updates happen but also the conversion of the associated voice update to MP3 for listening now happens automagically as well. I also fixed the hard time-limit, so updates shouldn’t cut off at 30 seconds like the one from Fort Collins did on the 24th. If you keep an eye on the page and everything goes well for me, you may catch an update from Lava Hot Springs later in the day. If you are especially bored (or are being paid by a Secret Government Agency or Vast International Conspiracy or Santa Claus to spy on me) I will try to do an update from there while sitting on the steps in view of the East Webcam. If so, I’ll be the tiny figure waving at the camera from the steps. If you happen to be watching at the right time, you might catch me there to gaze upon my magnificent pixellated spiffitude. Just don’t look directly at it or you may go blind…

Naturally, a live update from New Belgium Brewing Company is planned for tomorrow as well. After I return I can work on making my little application more interesting (embedded audio player, nicer presentation, maybe an embedded map, ability to come back later and attach related pictures…) and masssaged into a condition that wouldn’t be too embarassing to let others use. This “live neogeographical netcasting” thing is too much fun to keep just to myself. (I wonder how hard it would be to interface this with the Laconica microblogging system?…)

Further bulletins as events warrant…